Anorexia nervosa and bone metabolism

Anorexia nervosa and bone.

Anorexia nervosa (AN) is a condition of severe low weight that is associated with low bone mass, impaired bone structure, and reduced bone strength, all of which contribute to increased fracture risk. Adolescents with AN have decreased rates of bone accrual compared with normal-weight controls, raising additional concerns of suboptimal peak bone mass and future bone health in this age group. Ch...

Bone disease in anorexia nervosa.

Anorexia nervosa is a serious psychiatric disorder accompanied by high morbidity and mortality. It is characterized by emaciation due to self-starvation and displays a unique hormonal profile. Alterations in gonadal axis, growth hormone resistance with low insulin-like growth factor I levels, hypercortisolemia and low triiodothyronine levels are almost universally present and constitute an adap...

Disturbances of neurotransmitter metabolism in anorexia nervosa.

My understanding of anorexia nervosa is that it is ultimately a biological solution to an existential problem for an adolescent female and her family in the classical case. I t is not seen by the individual concerned as an affliction but rather, perhaps, as adaptive and egosyntonic. In order to protect her status the so-called patient will often successfully conceal major aspects of her feeling...

Effects of anorexia nervosa on bone density.

Sir, As arrhythmias occur when thrombolytics are administered, it is advised by Rawles (editorial, April Journal, p.l71) and by Hannaford and colleagues (April Journal, p.175) and elsewhere' that every doctor carrying thrombolytics outside hospital should also carry a defibrillator. I was not aware of this in 1992 when I considered participating in Hannaford and colleagues' study and it is not ...

Impaired bone health in anorexia nervosa